C.P.R. AND CEREBRAL PROTECTION
Definition: Cardiopulmonary Resuscitation
Includes: Basic Life Support (B.L.S.) and Advanced Cardiac Life Support (A.C.L.S.)
All part of a spectrum of Emergency Cardiac Care (E.C.C
Basic Life Support
- Improves survival following cardiac arrest
- Supports circulation +/- respiration when arrest has already occurred
- Includes Defibrillation
Advanced Cardiac Life Support
BLS + use of drugs/equipment to:
- Support airway/ventilation
- Establish intravenous access
- Give drugs
- Monitor
- Control arrhythmias
Goal of Resuscitation
- Return of victim to pre-arrest quality of life
- Return to pre-arrest state of health
Chain of Survival
- 5 critical interventions
- Not done or delayed => death
- Called the “Chain or Survival”
- Early Access
- Recognition: Collapse, unresponsiveness, arrested state
- Rapid arrival of help
- Early Cardiopulmonary Resuscitation
- The nearer to time of collapse resuscitation begins, the more effective
- Early Defibrillation
- Includes Automated External Defibrillator (A.E.D.)
- Early advanced care
- Access to drugs and trained medical staff
- Integrated Post-arrest care
- Access to multidisciplinary intensive care, coronary reperfusion facilities etc
Time!
4min – brain damage begins
4 – 6 min – brain damage likely
6min – brain damage certain
Prevention better than cure!
Unstable Patient (Pre-arrest)
- Pallor
- Sweating
- Cold, clammy extremities
- Impaired consciousness
- Hypotension (Sys <90)
- Chest pain
Unstable Patient – 1st steps
- Oxygen
- I.V. access
- 12 lead E.C.G. (if possible)
- Electrolytes – Correct
Arrhythmias
- Brady arrhythmias
- HR < 60
- Absolute bradycardia HR < 40
- Unstable?
- Sys BP < 90 mmHg
- HR < 40
- Ventricular arrhythmias
- CCF
- Sequence for Brady arrhythmias
- Tachyarrhythmias (with pulse)
C.P.R.
Definition:
- A series of actions performed on a victim of cardiac arrest that improve the chances of survival
- 1st published use of chest compressions 1960 – 14 survivors
JAMA 1960; 173:1064-67
- 1st use of defibrillator – 1962
- 1st published CPR guidelines – 1966
C.P.R. Today
- MAIN EMPHASIS
- High quality Chest Compressions
- Adequate rate and depth
- Complete recoil of chest wall
- Minimal interruptions
- Avoid excessive ventilation
- Post CPR care
- A.B.C. to C.A.B.
Reasons :
- Most survivors
- VF & pulseless VT
- Witnessed arrest
- Delay of chest compressions => reduced survival
- Airway control (Intubation) => greater level of ‘competence’ => delay
Cerebral Protection (Post-resuscitation)
- Mechanisms of Cerebral injury
- Cerebral ischaemia
- Failure of ion/energy pumps at cellular level
- Release of free radicals
- Reperfusion injury -> Release of inflammatory mediators:
- Leucotriene B
- Arachidonic acid
- Heat-shock protein
- Cerebral ischaemia
- Cerebral Protection
- Cooling – blunts cerebral ischaemic injury
- Normoglycaemia
- Avoid hyperoxia
- Barbiturate coma
Specific actions – Early CPR:
Recognition of arrest
- Immediate recognition of arrest and activation of emergency response system
- Unresponsive
- Not breathing or gasping
- Chest Compressions
- Rate – 100/min
- Depth – 5cm
- Complete chest wall recoil in-between
- Rotate person compressing every 2mts
- Minimal interruptions – maximum 10 seconds
Patient position for adequate chest compressions
- Patient horizontal & supine
- Head level or lower than heart
- Firm backboard
- Airway
- Head tilt/chin lift
- Jaw thrust – cervical spine injury
- If untrained in airway control – ‘Hands Only’ CPR
- Airway more important in asphyxial causes of arrest e.g. drowning and in children
- Breathing
CPR
- Ratio of compression:ventilation 30:2
- After advanced airway:
- Independent compressions 100/min
- Independent ventilation 10/min
- Early Defibrillation
- Once arrest recognized, collect AED/Defibrillator or send helper
- Defibrillation should not interrupt chest compressions for more than 10seconds
- Defibrillation more effective with quality chest compressions
- Defibrillation the key intervention for VF and pulseless VT
Types of Cardiac Arrest
- Cardiac arrest associated with 2 groups of arrhythmias:
- Shockable
- VF
- VT
- Non-shockable
- Asystole
- PEA
- Shockable
Sequence of actions
Shockable Rhythms (VF/VT)
- For a patient coming in with unwitnessed arrest, CPR for 2min, then defibrillation
- For in-hospital or witnessed arrest, immediate defibrillation
- Attempt defibrillation
- One shock
- CPR x 2min
- Check rhythm (<10sec)
- VF/VT persists
- 2nd shock
- CPR x 2min
- Check rhythm
- VF/VT persists
- Adrenaline 1mg
- 3rd shock
- CPR x2min
- Check rhythm
- VF/VT persists
- Amiodarone 300mg
- 4th shock
- CPR x2min
- Check rhythm
- VF/VT persists
- Adrenaline 1mg
- Shock
- CPR x2min
- Check rhythm
- Repeat sequence of Shock, CPR, rhythm, check. Give Adrenaline 1mg after every alternate shock/CPR sequence
- If organised electrical activity seen during rhythm check, feel for pulse
- Pulse present, post-resuscitation care
- Pulse absent, resuscitate as for non-shockable rhythm
- If Asystole, continue resuscitation as for non-shockable rhythm
Non-shockable Rhythms (Asystole/PEA)
PEA , Asystole & Slow PEA
- CPR 30:2
- Adrenaline 1mg as soon as i.v. access achieved
- Atropine 3mg only in asystole and slow PEA (<60/min)
- CPR 30:2 until airway secured
- Once airway secured
- Chest compressions are continuous
- Ventilation independent at 10 breaths per min
- Recheck rhythm after 2 min
- If no change
- Continue CPR
- Recheck rhythm ever 2 min
- Give adrenaline 1mg iv every 3 – 5 min
- If organised activity seen on ECG, check pulse
- Pulse
- Post resuscitation care
- No pulse
- Continue CPR, rhythm check, adrenaline cycle
- If VF or VT occurs switch to shockable rhythm sequence
As CPR goes on, remember to treat cause of arrest, if possible…
4Hs & 4Ts
The 4Hs
- Hypoxia
- Hypovolaemia
- Hyperkalaemia, hypokalaemia, hypocalcaemia, acidaemia, other metabolic disorders
- Hypothermia
The 4Ts
- Tension pneumothorax
- Tamponade
- Toxic substances
- Thromboembolism (PE/MI)
Summary
- CPR includes basic and advance life support
- Time is of essence in successful management of arrest
- Aim is to return patient to pre-arrest state through implementing “chain of survival”
- Recognition of pre-arrest rhythms key to preventing arrest
- Emphasis is on chest compressions, judicious ventilation, post CPR cerebral protection
- Proper sequencing important
- Treat possible causes as CPR goes on